Core Campus Mass Spectrometry Facility
Located within the Avera Health and Science Center’s laboratory and research wing, our facility is part of the Department of Chemistry, Biochemistry and Physics. The equipment is available to university faculty, staff, students and members of the public for a fee.
For availability and questions, please contact M. Nurul Islam.
Rates
| Instrument/Category | SDSU | Academic-non SDSU | Industry |
|---|---|---|---|
| LC-MS/MS: Sciex 5500+ TQ | $35/hour | $70/hour | $140/hour |
| GC-MS/MS: Agilent 8890 GC, 7000E TQ/MS | $30/hour | $60/hour | $120/hour |
| LC-MS: Thermo LTQ | $26.25/hour | $52.50/hour | $105/hour |
| *MS Facility Personnel Time | $175/hour | $262.50/hour | $525/hour |
*MS facility personnel time encompasses requested activities specific to individual users, including face-to-face training, mobile phase preparation, column preparation, sequence setup, sample preparation, method development consultation and other user-requested services which require mass spectrometry facility personnel time. This does not include troubleshooting, preventative maintenance, etc.
Equipment
LC-MS/MS
Shimadzu UHPLC-AB SCIEX QTRAP 5500 Mass Spectrometer System
Specifications
- Mass range: m/z 5-1,250
- Resolution (m/Δm): 2,000
- Accuracy: 1 ppm
- Scan speed: 20,000 Da/s
- Polarity switching in 50 ms
- Ionization source: Electrospray ionization
- Mass analyzer: Triple quadrupole
Common Applications
- Fast LC/MS
- Metabolite identification
- Detection and confirmation of low level pesticides
- Protein/peptide quantitation for biomarker verification and validation
- Ultra-fast and selective MRM scans mean you can target and quantify thousands of compounds in a single analysis.
Q-TOF LC-MS/MS (Accurate Mass)
Coming soon!
GC-MS/MS
Agilent 8890 GC + 7000E Triple Quadrupole
Specifications
- Mass Range: m/z 10-1050
- MRM Speed: 800 MRM transitions/s
- Minimum MRM Dwell Time: 0.5 ms
- Ionization Source: Electron Impact Ionization, HydroInert Ion Source
- Mass Analyzer: Triple Quadrupole
- Mode of Operation: EI (standard), CI (optional)
- Inlet: Split and splitless mode
- Sample Introduction: Liquid, headspace and SPME (solid-phase microextraction)
- Software: MassHunter (Data acquisition and analysis)
Common Applications
- Environmental contaminants such as PCBs, PAHs and pesticides
- Food safety, quality and authenticity
- Materials testing and consumer products, including structural and functional characterization of materials, and detection, identification, and management of impurities
- Energy and chemical applications, including crude oil refining and cleanup
- Pharmaceuticals, including impurities and APIs
- Forensic toxicology, including chemical warfare agents, trace analysis in fire debris, and drugs of abuse
Nanoflow LC-MS
Eksigent NanoLC-ThermoFisher LTQ Mass Spectrometer System
Specifications
- Mass range: m/z 150-2,000
- Resolution (m/Δm): 4,000
- Accuracy: 100 ppm
- Ionization source: Electrospray ionization
- Mass analyzer: Linear ion trap
Common Applications
- High-speed LCMS
- Proteomics/metabolomics
- Structural elucidation
- Protein identification and quantitative differential expression analysis
- Biomarker studies and post-translation modification identification
- Metabolite identification and quantification
Please direct all inquiries to our Mass Spectrometry Facility coordinator. If M. Nurul Islam is not reachable, contact the Department of Chemistry, Biochemistry and Physics.
